文档介绍：Clinical Oncology 23 (2011) 503e511
Contents lists available at ScienceDirect
Clinical Oncology
journal homepage: ate/clon
Original Article
Volumetric-modulated Arc Therapy in Head and Neck Radiotherapy: A Planning
Comparison using Simultaneous Integrated Boost for Nasopharynx and
Oropharynx Carcinoma
M. Johnston *, S. Clifford *, R. Bromley *y, M. Back *, L. Oliver *y, T. Eade *
* Radiation Oncology Department, Northern Sydney Cancer Centre, St Leonards, New South Wales, Australia
y
Institute of Medical Physics, School of Physics, Sydney University, New South Wales, Australia
Received 22 August 2010; received in revised form 18 November 2010; accepted 6 January 2011
Abstract
Aims: Volumetric-modulated arc therapy (VMAT) allows rapid delivery of radiotherapy. The aim of this planning study was to evaluate VMAT and dynamic
intensity-modulated radiotherapy (IMRT) using a simultaneous integrated boost technique
Patients and methods: puted tomography data from 10 patients with locoregionally advanced oropharynx or nasopharynx carcinoma were
selected. The prescription dose was 70, 63 and 56 Gy to the high-dose, intermediate-dose and low-dose planning target volume (PTV), respectively, and
planning parameters were according to Radiation Therapy Oncology Group IMRT protocols. VMAT and IMRT plans were calculated, and doseevolume histo-
grams were created for plan