文档介绍：Radiotherapy and Oncology 95 (2010) 149–152
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Radiotherapy and Oncology
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Volumetric modulated arc therapy
IMRT-based optimization approaches for volumetric modulated single arc
radiotherapy planning
Wouter Crijns *, Tom Budiharto, Gilles Defraene, Jan Verstraete, Tom Depuydt, Karin Haustermans,
Frank Van den Heuvel
Department of Radiotherapy, University Hospital Leuven, Belgium
article info abstract
Article history: This paper reports on an evaluation of 5 RapidArcÒ optimization approaches vs IMRT. This study includes
Received 23 July 2009 11 patients with adenocarcinoma of the prostate. Rectal Normal plication Probability is used
Received in revised form 8 January 2010 as a constraint in a dose escalation. RapidArcÒ rectal NTCP’s are lower than those of IMRT (p = ). This
Accepted 17 January 2010
allows a mean dose escalation of Gy([ Gy, Gy]).
Available online 18 February 2010
Ó 2010 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 95 (2010) 149–152
Keywords:
RapidArcÒ
VMAT
Dose escalation
Prostate cancer
Several treatment planning studies confirm a significant Planning
improvement an at risk (OAR) sparing using a RapidArcÒ
The treatment planning CT is acquired at least one week after
(RA) technique instead of intensity modulated radiation therapy
marker