文档介绍：第 37 卷第 3 期 2022 年 3 月 现代药物与临床 Drugs & Clinic Vol. 37 No. 3 March 2022 ·503·
HPLC-CAD H ) as the mobile phase for gradient elution. The flow rate was mL/min, the
column temperature was set at 30 ℃, and injection volume was 20 μL. The nebulization temperature of detector was set at 35 ℃, the
acquisition frequency was 10 Hz, and the filtration constant was . Results The linear ranges of eight components were —
、 — 、 — 、 — 、 — 、 — 、 — 、 — μg/mL,
respectively. The average recoveries were %, %, %, %, %, %, %, and %, and the RSD values were
%, %, %, %, %, %, %, and %, respectively. Conclusion The method can simultaneously determine 8 active
ingredients in Xiaojianzhong Tablets, and realizes the quality control of multi-index component, which provides a reference for the
standardization research of Xiaojianzhong Tablets.
Key words: Xiaojianzhong Tablets; oxypaeoniflora; albiflorin; paeoniflorin; liquiritin; isoliquiritin; cinnamic acid; HPLC-CAD
小建中片是由桂枝、白芍、炙甘草、生姜、大 具有温中补虚、缓急止痛的功效，用于脾胃虚寒、
枣组方而成，收载于《中国药典》2020 年版一部， 脘腹疼痛、喜温喜按、嘈杂吞酸、食少以及胃、十
收稿日期：2021-12-21
作者简介