文档介绍：醒脾养儿颗粒联合西药对小儿消化不良性腹泻免疫功能的影响及临床疗效分析
摘要 目的:觀察醒脾养儿颗粒联合西药治疗小儿消化不良性腹泻对免疫功能的影响及临床疗效。方法:选取2017年3月至2018年6月昆明市儿童医院儿科收治的消化不 in the observation group was % (52/55) higher than that of % (45/55) in control group ( P <).The improvement time of symptoms such as stool traits,diarrhea,bloating and fever in the observation group They were significantly shorter than the control group ( P <).Before treatment,the immune function indexes of 2 groups of children were not statistically significant ( P >).After treatment,CD3+,CD4+,CD8+,CD4+/CD8+ of children in the 2 groups were improved,but the observation group was significantly better than the control group,while the CD8+ level was lower than the control group ( P <).The incidence of adverse reactions in the observation group was % (3/55),and that in the control group was % (5/55) ( P >). Conclusion: Xingpi Yanger Granule combined with western medicine is effective in the treatment of dyspepsia in children with diarrhea and can significantly improve the cellular immunological function of is safe and worthy of clinical application. Key Words Xingpi Yanger Granules; Pediatric dyspepsia diarrhea; Immune function; Montmorillonite powder; Efficacy; Safety
中图分类号: 文献标识码:A doi: .1673-
小儿腹泻是多病因、多因素引起的疾病,消化不良性腹泻是其常见的疾病类型[1-2]。引起消化不良性腹泻病因多为喂养不当、食物过敏造成机体消化功能异常,从而导致小儿营养不良、生长发育障碍[3]。小儿消化不良性腹泻一般表现在大便性状上,正常小儿大便次数为1~2次/d,呈黄色条状物,而消化不良性腹泻患儿大便次数增加至4~6次/d,严重者可达10次/d,排便为稀水便、蛋花汤样便,有时是黏液便或脓血便,同时还伴随吐奶、腹胀、发热、精神不佳等症状。临床治疗消化不良性腹泻常联合用药,多以蒙脱石散+复合维生素B片治疗[4]。为进一步提高临床疗效,本研究以醒脾养儿颗粒+酪酸梭菌活菌散治疗消化不良性腹泻患儿,观察临床疗效及对免疫功能指标的影响,现报道如下。
1 资料与方法
一般资料 选取2017年3月至2018年6月昆明市儿童医院儿科收治的消化不良性腹泻患儿110例,根据随机数字表法分为观察组和对照组,每组55例。观察组中男30例,女25例;年龄1~7岁,平均年龄(±)岁;病程4~20 d,平均病程(±)d;体质量指数(BMI)9~17 kg/m2,平均BMI(±)kg/m2。对照组中男28例,女27例;年龄1~8岁,平均年龄(±)岁;病程4~23 d,平均病程(±)d;BMI 8~16 kg/m2,平均BMI(±)kg/m2。2组患儿一般资料比较,差异无统计学意义( P >),具有可比性。
诊断标准 患儿均按症状确诊为