文档介绍：网络首发时间：2022-04-25 14:28:03
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VP1 Gene of Porcine foot-and-mouth disease type O virus
DONG Jin-Jie1,2,3,4 WANG Hui-Bao2 WANG Fan2 DENG Rui-Xue2 LIU Ping2 CHEN Miao-Miao2
LI Yang-Fan2 ZHANG Yong1,4*
1 College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China; 2 China Agricultural Vet. Bio. Science and Technology
Co., Ltd., Lanzhou 730046, China; 3 Lanzhou Veterinary Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China; 4 Gansu
Key Laboratory of Animal Generational Physiology and Reproductive Regulation
* Corresponding author, ******@
Abstract Foot-and-mouth disease (FMD) is one of the most important infectious diseases causing
significant economic losses to the swine (Sus scrofa domesticus) industry. Vaccine immunization is still the one
of main ways to prevent and control foot-and-mouth disease. Because Foot-and-mouth disease virus is easy to
mutate, the antigen mismatch between candidate vaccine strains and epidemic strains will affect the immune
efficacy of vaccine and the effect of disease control. According to the molecular and functional characteristics
基金项目：甘肃省青年科技基金计划(20JR10RA47