文档介绍：第 卷第 期 医学信息
35 6 hina)
Abstract：
Epithelialovariancanceraccountsforapproximately90%ofallovariancancers,anditslethalityranksfirstamonggynecologicaltumors.
Withthecontinuousdeepeningoftumorgeneticresearch,mostscholarsbelievethattheoccurrenceofepithelialovariancanceristheresultofa
multi-factor,multi-step,andmulti-stagecomprehensiveeffect,whichiscloselyrelatedtoaseriesofgeneticchanges,andgeneshavebecomethenew
,whichcanbeusedasastandard
transcriptionfactorandanepigeneticregulator,
helptounderstandtheoriginandcarcinogenicpropertiesofovariancancer,makingPAX8proteinanexpecteddrugtargetforthetreatmentof
epithelialovariancancer,therebyeffectivelyinhibitingtumorcellproliferationandmetastasis,improvingpatientprognosis,andprolongingsurvival.
ThisarticlefocusesonthebiologicalcharacteristicsofPAX8,andintroducesindetailitsmechanismofactionintheprogressionandmetastasisof
epithelialovariancancer,prognosticrelevanceandtherapeuticeffects,withaviewtoclinicaldiagnosisofepithelialovariancancer,assessingthe
’
patient sdiseaseprogressionandprognosis,andguidingindividualizationprovideref