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地特胰岛素联合门冬胰岛素治疗妊娠糖尿病的临床效果.pdf

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地特胰岛素联合门冬胰岛素治疗妊娠糖尿病的临床效果.pdf

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地特胰岛素联合门冬胰岛素治疗妊娠糖尿病的临床效果.pdf

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文档介绍:河南医学研究 2022年 4月第 31卷第 7期 HENANMEDICALRESEARCH Apr.2022,Vol.31,No.7 ·1227·
naldiabetes
mellitus.Methods  A totalof63casesofgestationaldiabetesmellituscollectedfrom theFirstAffiliatedHospitalofHenan
UniversityofTraditionalChineseMedicinefromJanuarytoDecember2019wereselected.Thepatientsweredividedintocontrol
group(30cases)andobservationgroup(33cases)accordingtothetreatmentmethods.Thepatientsincontrolgroupwere
treatedwithinsulindetemir,whilethepatientsinobservationgroupweretreatedwithinsulindetemircombinedwithinsulin
aspart.Thetimeofreachingthestandardofbloodglucose,insulindosage,fastingbloodglucose,2-hourpostprandialblood
glucoseandhypoglycemiawererecorded.Omentin-1,homocysteine(Hcy)andtheindexofhomeostasismodelassessmentof
insulinresistance(HOMA-IR )werecomparedbetweenthetwogroupsbeforeandaftertreatment.Results  Thetimeof
reachingthetargetoffastingbloodglucoseand2-hourpostprandialbloodglucoseinobservationgroupwereshorterthanthosein
controlgroup,andthedosageofinsulinwaslessthanthatincontrolgroup(P<005).Aftertreatment,thefastingblood
glucoseand2-hourpostprandialbloodglucoseinthetwogroupsdecreased,whilethefastingbloodglucoseand2-hour
postprandialbloodglucoseinobservationgroupwerelowerthanthoseincontrolgroup(P<005).Theincidenceof
hypoglycemiainobservationgro