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单细胞转录组测序分析揭示腹膜透析患者透析流出液T淋巴细胞的改变.pdf

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单细胞转录组测序分析揭示腹膜透析患者透析流出液T淋巴细胞的改变.pdf

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文档介绍

文档介绍:新医学 2022 年4月第53卷第4期
292
T
Single-cell transcriptome analysis reveals changes of T lymphocytes in peritoneal fluid from peritoneal dialysis patients  Li
Yongjie, Sun Yuxiang, Lin Hongchun, Li Canming, Shang Hongli, Peng Hui. Department of Nephrology, the Third Affiliated Hospital
of Sun Yat-sen University, Guangzhou 510630, China
Corresponding author, Peng Hui, E-mail: pengh@ mail.
【Abstract】 Objective ff
To reveal the change trajectory of T lymphocytes in the dialysis e luent from peritoneal dialysis
( ) , - Methods
PD patients with the prolongation of PD time and to explore its relationship with PD associated peritoneal fibrosis. Cell
- ff ( -
classification was performed on the single cell transcriptome data of PD e luent cells from 10 PD patients 6 cases in the short term PD
- ) ,
group and 4 cases in the long term PD group obtained in our previous study and the data of T lymphocytes