文档介绍：实用妇科内分泌电子杂志 2022年第9卷第4期 •论 著.
DOI: involved in ubiquitin-like protein
ligase binding, DNA binding transcription factor binding, receptor ligand activity and other biological functions, lobelia chinensis
may aflfect the biological behavior of ovarian cancer by regulating PI3K-Akt and other signaling pathways. Molecular docking results
show that important compounds have a certain affinity for AKT1 and VEGFA proteins. Conclusion Lobelia chinensis is a potential
candidate drug for the treatment of ovarian cancer, which can exert anti-cancer protective effect through multi-target and multi­
pathway synergistic mechanism.
[Key words] Lobelia chinensis; Ovarian cancer; Network pharmacology; Active ingredients; Targets; Molecular docking
卵巢癌（ovarian cancer）以起病隐匿、缺乏早 和术后联合化疗为主，结合免疫治疗、放射治疗
期临床症状、复发率高为特点，是死亡率最高的 的综合治疗模式叫但由于患者体弱、化疗的不良
妇科恶性肿瘤目前卵巢癌的治疗方式是以手术 反应等原因，化疗常常会影响西医治疗的进程和
基金项目： 重庆市自然科学基金面上项目（编号cstc2020jcyj-nisxmX0208 ）
通信作者：彭媛，E-mail: ******@
1•论 著. Electronic Journal of Practical Gynecological Endocrinology