文档介绍：白芍总苷
白
芍
总
苷
研
究
进
展
erbaceous peony are total glycosides. In recent years due to the extraction technology and the improvement of detection method, the root of herbaceous peony root of herbaceous peony total glycosides research more and more thorough, in this paper the root of herbaceous peony root of herbaceous peony total glycosides extraction separation, content and research review.
key words 】: root of herbaceous peony total glycosides, extraction, purification, the content determination
Root of herbaceous peony from ranunculaceae plant peony Paeonia lactif loraPa ll1 dry root, alias gold peony, mainly produced in zhejiang, anhui, sichuan, etc. Root of herbaceous peony sex small cold, taste slightly bitter, acid to the liver, spleen, liver pain with flat, keep blood to regulate the menstrual function, gathered Yin hidroschesis effect and so on. The main root of herbaceous peony contain peony glucoside, paeonia lactiflora lactone glycosides, oxidation paeoniflorin, benzoyl paeoniflorin and single
terpenoids, root of herbaceous peony are total glycosides (TGP) [1], is also the root of herbaceous peony effective parts, have composed analgesic, anti-inflammatory and immune regulation effect. So for the root of herbaceous peony total glycosides in the extraction and separation of the content determination, the research is a necessity
1
白芍总苷
一．白芍化学成分研究
单萜及其苷类成分
1963 年, Shibata S. 等首次从白芍
的根中分离得到一种蒎烷单萜苷 , 命
[2]
名为芍药苷 paeoni-florin 。在
1972年,Kaneda M. 等用 X射线单晶衍
射法确定了它的结构 , 并同时分离得
到了羟基芍药苷 oxypaeoniflorin, 苯
甲酰芍药苷 benzoylpaeoniflorin 和
[3 ]
白芍苷 albiflorin 。
随后 ,Kitagawa 等从牡丹皮中分离得到苯甲酰羟基芍药苷
[4]
benzoyloxypaeoniflorin ，
Murakami N. 等分离出了氧化苯甲酰
[5]
芍药苷 等成分。 1981 年, 日本学
者 Shimizu M. 等从芍药的根中分离得
到了新的单萜芍药苷元***
[6]
paeoniflorigenone , 此外，
Shibutani S. 也得到了 gallotan-