文档介绍：1 保守治疗异位妊娠 112 例分析【摘要】目的探讨天花粉、 MTX 、米非司***保守治疗异位妊娠的使用价值。方法将 112 例病人随机分为三组, 天花粉肌注组 40 例,肌注天花粉 ~ ; MTX 组27 例, 1、3、5天 MTX 50mg+5%GS 500ml 静滴, 2、4、6天用 CF 12m g 解毒; 米非司***组45例, 米非司***组 50mg Bid ×3 天口服。结果三组血 HCG 下降至正常时间分别为( ± )天、( ± ) 天和( ± )天。三组比较 P﹤ ,三组成功率分别为 95% 、 % 和 % , 天花粉组与其他二组比较 P﹤ 。结论天花粉杀胚胎效果最好,但副作用较大, MTX 与米非司***组作用相似,副作用米非司***最小,应根据病人生育情况,血 HCG 高低选择最恰当的治疗方法, 提高异位妊娠保守治疗成功率, 减少药物副作用。【关键词】异位妊娠; 保守治疗; 绒毛膜促性腺激素 Analysis of ectopic pregnancy by conservative treatment in 2 112 cases 【 Abstract 】 Objective To explore the efficacy of trichosanthis, MTX and mifepristone in conservative treatment of ectopic 112 cases were randomly divided into three groups with 40 in group A recEived ~ of trichosanthis intramuscularly,27 in group B administered 50mg MTX and 5%GS 500ml intravenously at 1st,3rd , 5th day and detoxifying by 12mg of CF at 2nd , 4th , 6th day, 45in group C by taking 50mg of mifepristone orally for three Three groups of HCG were declined to the normal time of ( ± ) days,( ± ) days and ( ± ) days respectively. Comparing three groups P< ,cure rate of three groups were 95%,% and % respectively. Group pared with group B and group C,P< . Conclusion Trichosanthis has the best effect in killing embryo, but it has more side has similar efficacy with mifepristone, but mifepristone has less side effect. According to patients pregnancy and we should choose appropriate methods to raise the cure rate of ectopic pregnancy and lessen drugs side effect. 3 【 Key words 】 ectopic pregnancy; conservative treatment; β-HCG(human chorionic gonadotropin) 破裂型异位妊娠是妇科急腹症之一, 严重者可危及病人的生命,但随着人们保健意识的提高,定量血 HCG 的测定及***超声的应用, 大约 80% 异位妊娠可以在破裂前得到早期诊断。因此, 治疗倾向于保守[1]。如何较好地保留妇女生育功能, 成为临床工作者面临的一个问题, 我院分别用天花粉、氨甲蝶呤( MTX ) 及米非司***( 息隐) 作药物保守治疗,现报告如下。 1 资料与方法选择病例我院 2001 年1 月~ 2003 年3 月住院病人, 根据停经史、***流血史、腹痛等症状及妇科检查、血 HC G 测定、 B 超检查、诊断性刮宫术、后穹隆穿刺等辅助检查, 综合分析诊断为