文档介绍：First, two questions.
When do you get up
When do you go to bed
The biological clock is warning you
The molecular mFirst, two questions.
When do you get up
When do you go to bed
The biological clock is warning you
The molecular mechanism of controlling circadian rhythm
控制昼夜节律的分子机制
Reporter： Zhang Qing
The sunset but the rest.
日落而息
The sunrise makes.
日出而作
A phenomenon of the circadian rhythm / the biological clock
HOW DOES IT WORK IN GENE
The fruit fly :
sleeps during the day
howls during the night
WHY
The mutation 缺失 of a period gene in the body
周期基因
How to Realize Regulation of Circadian Rhythm precisly
如何实现昼夜节律的精确调控
What Is the Period Gene
The period gene encodes a protein called PER.
The timeless gene encodes a protein called TIM.
The double-time gene encodes a protein called DBT.
The PER protein will be transferred from the cytoplasm 细胞质 to the nucleus with the help of TIM protein at night.
The PER protein will degrade 降解 during the day.
The process of accumulation and degradation is about 24 hours, which corresponds to people's day and night.
DBT is to slow down the accumulation 积累 of PER protein, which allows precise regulation of circadian rhythms.
Open the lock requires two keys,
one called the PER protein
and the other called a TIM.
The frequency 频率 of opening the door is controlled by the DBT protein.
The process is liked as a lock and a key
First, heal some of the genetic diseases 遗传性疾病 .
Second, cure insomnia 失眠 .
Third, reveal the danger of staying up late.
What is The Use of This Finding
At last but not at least, we must let the body rest at the right time.
Pay attention to the biological clock, who is warning you
THANK YOU