肿瘤相关巨噬细胞、胶质瘤干...瘤组织中的表达及相关性研究 王晓英.pdf

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实用癌症杂志 2022 年 6 月第 37 卷第 6 期 The Practical Journal of Cancer June 2022 Vol 37 No． 6 【Abstract】 Objective To investigate the expression and correlation of CD133 CD68 and PD-L1 in different pathological
( ，
grades of human glioma． Methods 68 patients with gliomas were selected and divided into the low-grade group 34 cases who
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grade Ⅲ and Ⅳ and high-grade group 34 cases who grade Ⅰ and Ⅱ according to different pathological grades． The samples
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of the two groups were embedded in paraffin and the contents of CD68 and PD-L1 protein in gliomas of different pathological
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grades were detected by immunofluorescence method The expressions of CDl33 PD-L1 and CD68 mＲNA in glioma tissues of the
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2groups were detected by real-time fluorescence quantitative PCＲ and their correlation with clinicopathological grade was ana-
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lyzed． Ｒesults The expressions of CD133 CD68 and PD-L1 were significantly higher in high-grad