文档介绍:年 月 基础医学与临床
2021 12 Dec 结论 明显抑制 细胞的增殖
Slug、MMP2、MMP9 , ( <0. 05, <0. 01)。 LH MGC-803 ,
诱导细胞周期阻滞于 期 抑制细胞的迁移和侵袭 上调细胞内 基因表达水平
S , , miR-203 。
关键词: 石蒜碱 胃癌 迁移
; ; ;miR-203;Slug
中图分类号: ; ; 文献标志码:
R282. 71 R329. 25 R735. 2 A
Lycorine hydrochloride inhibits the proliferation,
migration and invasion of gastric cancer cell line MGC-803
1 2 2 2 2∗
BAO Mei-mei , XU Wen , WANG Chao , WANG Jia , MIAO Xiao-fen
(1. School of Physical Science and Technology, Soochow University, Suzhou 215006; 2. Department of Pathology,
Suzhou Traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou 215009, China)
Abstract Objective
: To investigate the effect of lycorine hydrochloride (LH) on the proliferation, migration and
Methods
invasion of human gastric cancer cell line MGC-803 and its possible mechanism. Cell proliferation ability