文档介绍:1894 临床肝胆病杂志第37 卷第8 期2021 年8 月 J Clin Hepatol,Vol.37 No.8,Aug.2021
·胰腺疾病·
胸腺肽 tobiliary Surgery,The Second Affiliated Hospital of Army Medical University,PLA,Chongqing
400036,China)
Abstract:Objective To investigate the association between perioperative immune status and postoperative infectious complications in eld-
erly patients undergoing laparoscopic pancreaticoduodenectomy (LPD),as well as the effect of thymosin a1 on postoperative complications.
Methods Related clinical data were collected from 43 elderly patients,aged 66 - 83 years,who underwent LPD in The Second Affiliated
Hospital of Army Medical University,PLA from June 2014 to June 2018,and the patients were divided into combination group with 22 pa-
tients (with the application of thymosin a1 in the perioperative period)and control group with 21 patients (without the application of thymo-
sin a1). Immune function parameters were observed before surgery and on days 3 and 7 after surgery,including serum levels of IgG,IgA,
and IgM,peripheral blood neutrophil - lymphocyte ratio (NLR),changes in CD3 + ,CD4 + ,CD8 + ,and CD4 + / CD8 + ratio,and the inci-
dence rate of postoperative infectious complications (pulmonary infection,pancreatic leakage,and abdominal infection). In addition,the
serum levels of C - reactive protein,interleukin - 2 (IL - 2),