文档介绍:介入放射学杂志 年 月第 卷第 期
—724 — 2021 7 30
【Abstract】 Objective To compare the curative effect of transcatheter arterial chemoembolization
(TACE) plus apatinib with that of TACE alone for middle - stage and advanced hepatocellular carcinoma
(HCC) by using propensity score matching method. Methods The clinical data of 265 patients with middle-
stage and advanced HCC, who were admitted to authors’ hospital to receive treatment during the period from
June 2016 to December 2017, were retrospectively analyzed. Based on the inclusion criteria, a total of 115
patients who had complete clinical data were enrolled in this study. According to the therapeutic scheme, the
patients were divided into combination group(n=29, receiving TACE plus apatinib) and control group(n=86,
receiving TACE alone). By using propensity score matching method with 1∶1 ratio, the clinical effects of the two
groups were analyzed. The overall survival(OS) and progression-free survival(PFS) were the main observation
indicators, the tumor response and apatinib-related adverse reactions were the minor observation indicators.
Results A total of 25 pairs were matched, and the baseline data between groups were comparable. After
pair-matching, the 1-year, 2-year and 3-year su