文档介绍：Explore Changes in shenqi pill dose ratioof renal function in renal
injury of rats
Speciality: TCM clinic basis-JinGuiYaoLue
Author:Zheng Xinggang
Tutor: Hanhua
Abstract
Objective: To study the influence of renal function and renal pathology of renal
injury rats by gentamicin with the different shenqi pill dose pairing,discuss the changes in
kidney pill quantity influence of ratio of drug, in order to seek the the optimal dose ratio of
kidney pills. Methods: Manufacturing renal injury rats model by intraperitoneal injection
of gentamicin,then treat with the different shenqi pill dose pairing,observe the rats’ serum
urea nitrogen (BUN), serum creatinine (Cr) and renal biopsy. Results: 1. During the model
process, the rats appear burnout, spirit dispirited, crowded together, reduced activities,
afraid of cold, no gloss of fur, clear and loose stool and other symptoms. After finishing the
model, treat the groups of rats with shenqi pill, their above symptoms gradually improving.
2. BUN, Cr and renal biopsy observation display: the different shenqi pill dose pairing to
kidney injury rats caused by gentamycin have different effects of renal function.
Conclusion: The changes of cortex moutan radicis , cinnamon and aconite dose pairing
have greater impact to renal injury rats’ BUN、Cr, the best ratio of shenqi pill to against
experimental renal injury is: dried rehamnnia root 8 portions, macrocarpium officinalis 4
portions, yam 4 portions, poria 3 portions, alisma orientalis 3 portions, cortex moutan
radicis 2 portions, cinnamon 2 portions, aconite 2 portions.
Key words
experimental study
shenqi pill; dose ratio change; renal injury; theoretic discussion;
目
录
引
言............................................................................................................................... 1
理论探讨............................................................................................................................... 2
一、肾气丸方