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Big-Data-Analytics-In-Medicine-大数据分析-公开课ppt课件.pptx

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BigDataAnalytics
InMedicine
BigDataAnalyticsandDrugSideEffects
2
BigDataAnalyticsstudyhasfoundanassociation
betweentheuseofproton-pumpinhibitors质子泵抑制剂andthe
likelihoodofincurringaheartattack
[Shah,,.]
HeartAttack
ElectronicHealthRecords(EHRs)ofnearly3million
peopleandtrillionsofpiecesofmedicaldata
BigData
Alzheimer’sDiseaseEvolution
BigDataAnalyticsandDiseasePredisposition体质
BigData
Researchersanalyzedmorethan7,700brain
imagesfrom1,171peopleinvariousstagesof
Alzheimer'sprogressionusingavarietyof
techniquesincludingmagneticresonanceimaging
(MRI)andpositronemissiontomography(PET).
BigDataAnalyticsstudyhasfoundthatchangesin
bloodflowaretheearliestknownwarningsignof
Alzheimer's.

3
BigData:MedicalImage
LargevolumesofdataproducedbyImagingTechniques
Volumeofmedicalimagesisgrowingexponentially
Annotateddataorstructuredmethodstoannotate
medicalimagesischallenging
BigDataAnalyticalMethodsallowfortheinterpretability
ofdepictedcontents
ScalableMethodsforcollecting,compressing,sharing,
andanonymizingmedicaldata
MedicalImageProcessingfromBigDataPointofView
4
ElectronicHealthRecords(EHR)fromBigDataPointofView
BigData:ClinicalData
LargevolumesofClinicalDatathatneedstobe
stored,retrieved,andaggregated
ScalableMethodsforcollecting,compressing,
sharing,andanonymizingmedicaldata
ScalableMethodsforsignalprocessingandfor
developingBigDatabasedclinicaldecisionsupport
systems(CDSSs)
5
GenomicsfromBigDataPointofView
BigData:GenomicsData
HumanGenomeconsistsof30,000to35,000genes
ScalableMethodsforpathwayanalysisandforthediscover
associationsbetweenobservedgeneexpressionchangesand
predictedfunctionaleffects
ScalableMethodsforReconstructionofMetabolicand
RegulatoryNetworks
6
7
ChallengesofBigDataManagementandAnalytics
8
ChallengesofBigDataManagementandAnalytics
9
BigDataPipeline
PrecisionMedicine
14
Medicalmodelthatproposesthe
customizationofhealthcare,withmedical
decisions,practices,orproductsbeing
tailoredtotheindividualpatient