文档介绍：现代生物医学进展 gress in Modern Biomedicine ·2339 ·
阿奇霉素联合痰热清治疗小儿肺炎支原体肺炎疗效观察
严峻易静波肖雪花
(湖南师范大学附属湘东医院放射科湖南醴陵 412200)
摘要目的:探讨阿奇霉素联合痰热清治疗小儿肺炎支原体肺炎(mycoplasma pneumoniae pneumonia, MPP)的临床疗效。方法:124
例 MPP 患儿随机分为对照组(56 例)与治疗组(68 例),其中对照组给予阿奇霉素序贯治疗,治疗组则在此基础上另外给予痰热清
治疗。采用双抗体夹心 ELISA 法、免疫比浊法分别检测治疗前后所有 MPP 患儿血清 CRP、IL-6 与 TNF-α含量。同时观察比较两
组临床疗效、症状体征及不良反应情况。结果:①经治疗所有患儿血清 CRP、IL-6 与 TNF-α浓度均明显下降(P<),治疗组与对
照组间差异无统计学意义(P>)。②治疗组总有效率为 %,显著高于对照组 %的总有效率(P<)。③治疗组退热时
间,咳嗽和肺啰音消失时间均显著短于对照组(P<)。④治疗组不良反应发生率明显低于对照组,差异具有统计学意义(P<0.
05)。结论:痰热清联合阿奇霉素序贯疗法治疗小儿 MPP 安全有效,值得进一步推广。
关键词:肺炎支原体肺炎;阿奇毒素;痰热清
中图分类号: 文献标识码:A 文章编号:1673-6273(2010)12-2339-03
Observation of the Curative Effect of bined with
Tanreqing in treating Child with Mycoplasma Pneumoniae Pneumonia
YAN Jun,YI Jing-bo,XIAO Xue-hua
(The affiliated Xiangdong hospital of Hunan Normal University, 412200,China)
ABSTRACT Objective:To investigate the clinical curative effect of bined with Tanreqing in treating child with
mycoplasma pneumoniae pneumonia (MPP). Methods:124 cases of children with MMP were randomly divided into treated group (68
cases) and control group (56 cases). The control group were given Azithromycin therapy, while the treated group was added with
Tanreqing. The serum levels of CRP, IL-6 and TNF-α were measured with immunoturbidimetry and ELISA respectively. The clinic