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儿童贫血全英文课件.ppt

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儿童贫血全英文课件.ppt

上传人:yzhluyin9 12/1/2022 文件大小:2.48 MB

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文档介绍:该【儿童贫血全英文课件 】是由【yzhluyin9】上传分享,文档一共【93】页,该文档可以免费在线阅读,需要了解更多关于【儿童贫血全英文课件 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。Anemiainchildhood (小儿贫血)
Diseaseof hematopoieticsystem
infantileanemia
(1)nutritionalirondeficiencyanemia(IDA)
(2)nutritionalmegaloblasticanemia
Primary/immunitythrombocytopeniaPurpura(ITP)
Leukemia
Embryostage
Mesoblastichaematogenesis:3wsbegin,8wsweaken,12-15wsdisappears。
liver:8wsbegin,6monthsgraduallyweaken,erythroblast、granularcellandmegakaryocyte.
Embryostage
3、spleen:12wsbeginerythrocyte,granule,
lymphocyte
4、Haematogenesisoflymphaticorgan
::11ws
Embryostage
5、myelo-haematopoiesis:6mons
Haematogenesisfunctionemphasis,makevariouskindsofbloodcells,uniquehematogenicorganafterbirth.
Haematopoiesispostnatal
1、marrow:
2、extramedullary:whenrequirementofhaemopoiesisincrease,liver、spleen、lymphadenectasis,hepatomegalyandsplenomegaly,incirculatingblood
immatureerythrocytesandgranulocytes.
Physiologicalhaemolysis
Normalnewbornshavehigherhemoglobin(HB)andhematocritlevelsandashortenedsurvivalperiodofthefetalRBCscontributes tothedevelopmentofphysiologicanemia.
Physiologicalhaemolysis
erythropoiesisabruptlyceaseswithonsetofrespirationatbirth,whenthearterialoxygensaturationrisestoward95%.levelsoferythropoietin(EPO)arelow.
EPOhasadecreasedhalf-.
thesizableexpansionofbloodvolumethataccompaniesrapidweightgainduringthefirst3mooflifeaddstotheneedforincreasedRBCproduction.
Redbloodcell(RBC)
Termnewbornshavearedcellmassthatishigherthanatanyothertimeoflife.
anappropriateconditionforthelowoxygenenvironmentofintrauterinelife.
×1012~×1012,hemoglobinconcentrationisabout150~220g/Latbirth.
TheRBCandhemoglobinconcentrationinpreterminfantsareslightlylowerthanthoseinterminfants.
Redbloodcell(RBC)
Thewiderangeofhemoglobinconcentrationisaccountedforby:
Variationinhowrapidlytheumbilicalcordisclamped.
Aninfant’spositionafterdelivery.
Ifcordclampingisdelayedandthebabyisheldlowerthanplacenta,bothhemoglobinandbloodvolumeareincreasedbyaplacentaltransfusion.