文档介绍:该【covid-19 reinfection – what could the absence of evidence suggest 2021 jack west 】是由【夸客客】上传分享,文档一共【3】页,该文档可以免费在线阅读,需要了解更多关于【covid-19 reinfection – what could the absence of evidence suggest 2021 jack west 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。InfectiousDiseases
ISSN:(Print)(Online)Journalhomepage:
Covid-19reinfection–whatcouldtheabsenceof
evidencesuggest?
JackWest
Tocitethisarticle:JackWest(2021):Covid-19reinfection–whatcouldtheabsenceofevidence
suggest?,InfectiousDiseases,DOI:.1910339
Tolinktothisarticle:/
Publishedonline:13Apr2021.
Submityourarticletothisjournal
Articleviews:278
Viewrelatedarticles
ViewCrossmarkdata
FullTerms&Conditionsofaccessandusecanbefoundat
?journalCode=infd20
INFECTIOUSDISEASES,/
2021;,
,1–2
EDITORIALCOMMENTARY
Covid-19reinfection–whatcouldtheabsenceofevidencesuggest?
Inthepresentissue,under‘ReinfectionofSARS-COV-2–(EstimateoftrueCovid-19reinfectionsas10,000times
Analysisof23CasesfromtheLiterature’)
[1]analyzedtheexistingconfirmedreinfectionsof230,000/115,000,000¼(%oftotalinfections)
Covid-19todate,searchingfortrendsinseverityand(C)23Â100,000¼2,300,000
(EstimateoftrueCovid-19reinfectionsas100,000
paperaddressesthecurrentuncertaintysurroundingtimesgreaterthantheliteraturereported23reinfec-
)
thatthecurrentabsenceoflargenumbersofconfirmed2,300,000/115,000,000¼(2%oftotalinfections)
Covid-19reinfectionssupportsapositiveoutlookatthisAllofthevaluesintherangewouldbesmallpropor-
Todateover115millionconfirmedcaseshavebeenanapproximatescaletothereinfectionproblem,cur-
recordedoveraperiodofalittlemorethanoneyearrentlyofamagnitude50-to5000-timessmallerthanini-
(WHOCoronavirus(COVID-19)DashboardjWHOtialinfections.
CoronavirusDisease(COVID-19)Dashboard,nodate)[2].Thelimitedtimelinethatthesedatapopulatemust
Clearconsensusdoesnotyetexistregardingthedur-
ationofimmunitythatcanbeexpectedfollowinganbetweenoneandtwoyears,thefractionofcasesrepre-
aperiodofonlyweekstomonths,populationsexposedmonthstofollow.
tohighCovid-19prevalence;suchastheUnitedConcretedatainthisareahasonlyrecentlybecome
Kingdom,wouldalreadyhaveampleopportunityforre-available,withpre-printdatafromtheUKbasedSIREN
Thiscommentaryarguesthatcautiousinferencesreinfectioninahigh-riskenvironment,trackingover
aboutreinfectionriskcanalreadybemadefromthecur-20,
<1%[3].
The23casesidentifiedbythereviewrepresentatinyThisvaluefallsmidwaythroughtheestimatedrangesof
proportionoftotal(115million)confirmedcases,reinfectionproportiondiscussedabove,andasmore
,itwasalsofound
,ifthese23casesrepresentonly1thatovertwothirdsofreinfectionsareasymptomatic
in1000;1in10,000;or1in100,000ofthetruenumber[4].Thisfindingcouldhelptoexplainthepaucityof
ofreinfections,theproportionoftotalCovid-19casesconfirmedreinfectioncasesreported,andwhyestimates
representedbyreinfectionswouldremainaslimminor-oftruenumbersmustbethousandsoftimesgreater
.
(A)23Â1000¼23,000Insummary,whilst‘ReinfectionofSARS-COV-2–
(EstimateoftrueCovid-19reinfectionsas1,000timesAnalysisof23CasesfromtheLiterature’demonstrates
greaterthantheliteraturereported23reinfectioncases)thewidegeographicreachofCovid-19,thescarcityof
23,000/115,000,000¼(%oftotalinfections)confirmedcasesavailablesupportsaviewpointthat
(B)23Â10,000¼230,
pre-printdatacorroboratesthis,butallconclusionsmustthanantibodynegativehealthcareworkers?Largemulti-
bemadecautiouslyonlyoneyearintothepandemiccentreprospectivecohortstudy(theSIRENstudy),England:
:.
.
Disclosurestatement[4]—butcouldstill
:-
Nopotentialconflictofinterestwasreportedbytheauthor(s).021-00071-6
References
JackWest
[1]RobertsAT,PianiF,LongoB,-COV-2UniversityHospitalsDorsetNHSFoundationTrust,Dorset,UK
–.******@
[2]WHOCoronavirus(COVID-19)
disease(COVID-19)(Switzerland):WHO;;revised23March2021;accepted24
[cited2021March13].Retrievedfrom:
[3]HallV,FoulkesS,CharlettA,
healthcareworkershavelowerSARS-CoV-2infectionratesß2021SocietyforScandinavianJournalofInfectiousDiseases