文档介绍：Medical Microbiology
Chapter 1 Introduction
[Requirement]
Master the definition of anism
Master the classification of anism
[Class hour: 1 hours ]
[Outline]
Microbes
Definition (anism)
Classification
categories according to structure
Non—cellular type
Virus: no cellular structure
Parasite in living cell
Only contain one kind of nucleic acid molecule , DNA/RNA
2)Prokaryotic type
No nuclear membrane or mitotic apparatus nuclear region can be seen ,
composed of DNA.
No separate internal membrane anelles .
Bacterium Mycoplusma
Chlamydia Riclcettsia
Spirochetes Actinomycetes
3) Eulcaryotic type
intracellular membrane —anelles
Fungi : hyphae
yeast
nucleus : two membrane layers
Endoplasmic Reticulum (ER) rough ER
Smooth ER
Mitochondria
of anisms: 1) In environments.
2) In anisms
II Microbiology
1 .research objective : Pathogenic Microbes
1)biological properties
2)pathogenesis and immune response
3) Diagnosis and protection
History
Leeuwenhock : invent Microscope in 1674 .
Pasteur : pasteurization , ine
Koch : solid medium purify bacteria
Pathogenic microbe criterion
Lister : disinfection aseptic technique
Iwanovsky virus.
Modern M
Most bacteria were controled by antibiotics. Drug-resistant strains—> resistence plasmid.
Normal flora—opportunistic pathogens
(flora disequilibrium super-infection )
Hospital acquired infections.
New bacteria : Helicobacter pylori—chronic gastritis.
Viral research made progress.
AIDS
New diagnostic techniques .
ELISA
PCR :polymerase chain reaction.
New type ine .
Microbial genomic program, MGP .
Chapter 2 Bacterial shape and structure
[Requirement]
Master the structure of bacteria and their functions
Master the following concepts :
plasmid 2. flagellum 3. pillus 4. capsule
-form bacterium 6. mesosome 7. haride(LPS)
Understand the size and shape of bacteria.
[Class hour: 3 hours ]
[Outline]
Section I . Bacterial Mo