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多伦多病童医院脑干胶质瘤.ppt

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多伦多病童医院脑干胶质瘤.ppt

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多伦多病童医院脑干胶质瘤.ppt

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文档介绍:该【多伦多病童医院脑干胶质瘤 】是由【相惜】上传分享,文档一共【97】页,该文档可以免费在线阅读,需要了解更多关于【多伦多病童医院脑干胶质瘤 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。PaediatricBrainstemTumours
.
.
amongbrainstemgliomas
A tectalglioma
B focalmidbraintumor
C focalintrinsicpontineglioma
D dorsal/exophyticglioma
E diffuseintrinsicpontineglioma*
F focalmedullaryglioma
G cervicomedullaryglioma
AFewImportantDistinctions
*aformofhighgradeglioma,akinto
anaplasticastrocytomaor
glioblastomamultiforme
.
BrainstemGliomas
Lowgradegliomas
Notcommon!
Focalexophytic
Cervicomedullarytumours
DiffuseIntrinsicBrainstemTumours
10-15%ofallbraintumours
25%ofthemortalitybybraintumourinchildren
Atypicalbrainstemtumours
Atypicalbrainstemlesions
Brainstemtumoursininfants
.
Lowgradegliomaofthebrainstem
Clinicalsymptoms
Oftenlongpresentinghistory
Progressivemotordeficitorataxia
Cranialnervedeficitsareinfrequent
Radiologicalcharacteristics
Majorityarefocalandexophitic
Enhancingtumours
.
DiagnosisandmanagementofLGG
Needabiopsy/resection
Oftenpilocytic
Resultneedstobecorrelatedwiththeclinicalandradiologicalcharacteristics
Surgicalresection(evenincomplete)canleadtosustainedremissionorcure
.
August2001
August2006
October2014
.
August2000
December2001
.
DiagnosisandmanagementofLGG
Postoperativemanagement
Eitherimmediatelyaftersurgery
Oratthetimeofprogression
Radiationorchemotherapy?
Noclearanswer
Radiationstillstandardtreatment
Chemotherapyworks
.
December2001
December2002
Lowgradegliomaofthebrainstem:
chemotherapywithweeklyvincristineandcarboplatin
.