文档介绍：· 14 · 中西医结合学报 2004 年 1 月第 2 卷第 1 期 J Chin Integ r Med, Jan 2004 , Vol .2, No .1
胰岛素抵抗的发病机制及中西医结合防治策略
王树海, 王文健
(复旦大学附属华山医院中西医结合研究所, 上海 200040 )
[摘要] 胰岛素抵抗(insulin resistance ,IR) 是多种代谢性疾病共同的病理生理基础, 其确切发病机制目前尚无定论。近年来
脂肪细胞内分泌功能和炎症反应参与 IR 的发病机制及胰岛素增敏剂的研究成为新的研究热点。中医药对胰岛素抵抗的病
机及治疗也进行了探索,为中西医结合防治胰岛素抵抗奠定了基础。
[关键词] 胰岛素抵抗; 发病机制; 中西医结合疗法
[中图分类号] R587 .3 [ 文献标识码] A [ 文章编号] 1672-1977(2004)01-0014-03
Pathogenesis of insulin resistance and prevention and treatment strategy of integrated traditional Chinese and
western medicine
WANG Shu- Hai, WANG Wen-Jian
(Institute of Integrated Traditional Chinese and Western Medicine, H uashan H ospital, Fudan U niversity, Shanghai 200040,
China)
ABSTRACT Ins ulin resistance is mon pathophysiologic basis of multiple metabolic diseases , but the exact mechanism
of ins ulin resistance is still unclear presently . In the past few years , studies on the pathogenesis of insulin resistance, in which
the endocrine function of adipocyte and inflammation reaction participate , as well as the insulin- sensitizing drugs have e
the new hotspot . The exploration on pa thogenesis and treatment of insulin resistance in traditional Chinese medicine has estab-
lished a foundation for the prevention and trea tment of insulin resistance in integrated traditional Chinese and western medicine .
KEY WORDS insulin resistance ; pathogenesis ; integ