文档介绍：肺癌指骨转移临床分析
肺癌以指骨转移为首发症状17例临床分析韩俊庆[1] 韩春燕[2] 毕迎惠[2] 丁晓[2] 王兴文[1] 盛巍[1] 李冠桢[1]
[1] 250021 济南山东省立医院肿瘤中心;[2] 250012 济南山东大学医学院。
[摘要] 目的:探讨原发性肺癌以指骨转移为首发症状的临床特点及发生指骨转移的机理;方法:对1991年至2007年期间有关文献报道的以指骨转移为首发症状的原发性肺癌患者的文献资料进行综合分析;结果:本文及文献报道的以指骨转移为首发症状的17例原发性肺癌患者中,其转移病灶位于左手指骨者7例,右手指骨者9例,双手指骨者1例,指骨转移病灶的数量在两手之间的分布大致相等,除3例患者其转移病灶位于指骨近节外,其余患者的转移病灶均位于其指骨末节;有6例病人的患病手指既往曾有外伤史;结论:传统的机械-解剖学说和种子-土壤学说的观点均不能解释原发性肺癌发生指骨转移的机理,临床上如遇久治不愈的手指软组织炎症,应想到有肿瘤细胞转移至此的可能性。关键词:肺癌;首发症状;指骨转移;
The clinical analysis of 17 cases with bronchogenic carcinoma of fingers metastases as its first symptom HAN Junqing[1], HAN Chunyan[2], BI Yinghui[2], DING Xiao[2], WANG Xingwen[1], SHENG Wei[1], LI Guanzhen[1]. Department of Oncology, Shandong Provincial Hospital, Jinan 250021;Medicine School, Shandong University, Jinan 250012,China.
[Abstract] Objective Research the clinical characteristics of primary bronchogenic carcinoma with metastases of phalanges of fingers as its first symptom and the mechanism of tumor metastasis to phalanges of fingers. Methods Literature on primary bronchogenic carcinoma with metastases of phalanges of fingers as its first symptom published between 1991 and 2005 was reviewed, and was synthetically bining with the clinical data of two such patients treated in our hospital. Results 16 patients reported in the reviewed literature and this article had primary bronchogenic carcinoma with metastases of phalanges of fingers as its first symptom. 7 patients’ metastatic lesions located in their
phalanges of left hands, 8 right hands and 1 both hands. The distribution of the quantity of the phalangeal metastases between two hands was almost equal. 3 patients’ metastatic lesions were situated in proximal phalanges of fingers, and the rest in distal. 6 patients’ ill fingers had had trauma history. Conclusions Neither the traditional machine-anatomy theory nor seed-soil theory could explain the mechanism of primary bronchogenic carcinoma metastasizing to phalanges of fingers, If patients wi