文档介绍：TP方案新辅助化疗治疗局部晚期食管癌的疗效观察
[摘要]目的探讨TP方案新辅助化疗治疗局部晚期食管癌的疗效,为局部晚期食管癌的治疗提供可靠的依据。方法选取2014年1月~2016年3月在我院住院的局部晚期食管鳞癌患者34例进行研究,所有患者均采用TP方案新辅助化疗,每2周期化疗后评价疗效及不良反应,2~4个周期后行手术治疗,无法手术患者予行根治性放疗,观察患者治疗后的疗效及安全性。结果 34例患者经新辅助化疗后完全缓解3例,%,部分缓解15例,%;稳定15例,%,疾病进展1例,%,%。成功行根治性手术23例,%;治疗期间1级不良反应12例,%,2级8例,%,3级3例,%;4级1例,%;无5级不良反应。结论 TP方案新辅助化疗治疗局部晚期食管鳞癌可有效缩小肿瘤体积,提高手术切除率,不良反应轻,值得临床推广应用。
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[关键词]局部晚期食管癌;新辅助化疗;TP方案
[中图分类号] [文献标识码] A [文章编号] 1674-4721(2017)06(b)-0057-04
[Abstract]Objective To explore the efficacy of TP regimen adjuvant neoadjuvant chemotherapy in the treatment of locally advanced esophageal carcinoma,and to provide a reliable basis for the treatment of locally advanced esophageal 34 patients with locally advanced esophageal squamous cell carcinoma who were hospitalized in our hospital from January 2014 to March 2016 were patients underwent neoadjuvant chemotherapy with TP efficacy and adverse reaction were evaluated every 2 -4 cycles after surgery,surgery can not be given for radical radiotherapy patients,and efficacy and safety of patients after treatment in patients were Among 34 patients,3 cases plete remission after neoadjuvant chemotherapy,accounti