文档介绍：酸枣仁功效成分测定及改善睡眠保健功能的研究论文
黄维,金邦荃,程光宇,杨云峰,冯波,吴京燕
【摘要】目的研究酸枣仁功效成分的含量对小鼠睡眠的改善作用及改善睡眠的初步机理。方法用化学方法测定酸枣仁粗多糖、总黄***和总皂苷的含量,高效液相色谱法测定酸枣仁皂苷 A 的含量。通过直接睡眠实验、延长戊巴比妥钠睡眠时间实验、戊巴比妥钠阈下催眠剂量实验和巴比妥钠睡眠潜伏期实验,比较低、中、高3个剂量(570 .freelg/kg)酸枣仁粉剂对小鼠睡眠的影响,并且用荧光法测定小鼠脑中 5-羟色***含量。 g/100 g, g/100 g,总黄*** g/100 g。中剂量样品(1 000 mg/kg)具有改善睡眠的作用,酸枣仁改善睡眠与小鼠脑中5-羟色***含量具有相关性。结论酸枣仁粉剂功效成分的含量较高,具有改善睡眠的作用,改善睡眠与小鼠脑中5-羟色***含量有关。
【关键词】酸枣仁; 功效成分; 改善睡眠; 5-羟色***
Abstract:ObjectiveTo study the content of functional position of Semen Ziziphi Spinosae and its effect of improving content of coarse amylose, total flavone and total jujuboside easured by chemical processes. The content of jujubosideA easured by HPLC. The effect of sleep improvement of the three dosages(570 mg/kg,1000 mg/kg and 2000 mg/kg)of Semen Ziziphi Spinosae ents of sleep-induced directly, prolonging sleeping time induced by pentobarbital sodium, affecting mouse sleeping rate under the threshold hypnogenesis dosage of pentobarbital sodium and affecting sleeping delitescence induced by tobarbital sodium. The content of 5-HT in the brain of mouse easured by fluorescence assay. ResultsThe content of total jujuboside in Semen Ziziphi Spinosae iddle dosage (1 000 mg/kg) could improve the sleep quality, and sleep improvement had high relativity proved by Semen Ziziphi Spinosae, and it has relation ouse.
Key en Ziziphi