妇科临床医学论文 子宫肌瘤临床论文.doc

文档介绍：妇科临床医学论文子宫肌瘤临床论文
米非司酮联合桂枝茯苓加减丸治疗子宫肌瘤的临床观察
【摘要】目的对比米非司酮与桂枝茯苓加减丸联合用药或单独用药治疗子宫肌瘤的疗效。方法回顾性分析98例子宫肌瘤患者治疗方案及疗效。31例患者口服米非司酮片(米非司酮组);33例患者口服桂枝茯苓加减丸(桂枝茯苓丸加减丸组);34例患者同时服用两种药物(联合用药组),均连续用药3个月。检测子宫肌瘤体积以及血清卵泡刺激素(FSH)、黄体生成素(LH)、雌激素(E2)及孕酮(P)的浓度。结果联系用药3个月之后,3组患者月经量、经期时间、痛经以及腰部酸胀等症状较治疗前明显改善,其中联合用药组月经量较其他两组减少更为明显。米非司酮组、桂枝茯苓加减丸组、%、%%,血清FSH、LH、E2、P的浓度较治疗前均明显降低(P<),随访1年发现桂枝茯苓加减丸组及联合用药组无反弹。结论米非司酮与桂枝茯苓加减丸联合用药治疗子宫肌瘤疗效明显优于单独用药,值得临床推广应用。
【关键词】米非司酮;桂枝茯苓加减丸;子宫肌瘤

Clinical effects bined administration of Mifepristone and guizhi fuling wan(GFW)onhysteromyoma
WANG Yuan ,SHI Xiao-yan. department of gynecology, Affiliated Hospital of Yan’an University, Yan’an 716000, China
【Abstract】 Objective pare the clinical effects of bination of Mifepristone and GFW on hysteromyoma to that of Mifepristone or GFW alone. Methods y-eight patients with hysteromyoma consecutively received administration of Mifepristone and(or)GFW for 3 month. Moreover, the volume of hysteromyoma and serum concentrations of follicle stimulating hormone(FSH), luteinizing hormone(LH), estrogen(E2)and pregnendione(P)were detected pre-and post-treatment. Results Menstrual blood volum(MBV), bradymenorrhea, menalgia, fort in hypogastrium were generally ameliorated after 3 month pared with that of pre-treatment, especially in patients received bination as for MBV. Furthermore, administration