文档介绍:山东中医药大学硕士学位论文当归四逆汤加减方治疗Bell麻痹的临床研究姓名:苗莉莉申请学位级别:硕士专业:中医内科学指导教师:胡志强 20070420 提要目的:观察当归四逆汤加减方治疗Bell麻痹的临床疗效,以寻求治疗Bell麻痹的新思路及有效方药。方法:临床研究,将60例Bell麻痹患者随机分为当归四逆汤治疗组与大活络胶囊对照组,两组均治疗2l天。观察治疗前后两组House-Brackmann (H—B)分级、面部残疾指数评分(包括躯体功能FI)IP评分和社会生活功能FDIS 评分)、电生理学检查面神经电图波幅损失百分比以及瞬目反射RI波潜伏期等指标的变化。结果:经统计学分析,%,%, 两组比较总有效率有显著性差异(P<)。治疗后治疗组在H—B分级、FDIP评分等指标的改善方面均优于对照组(P<),而在FDIS评分变化的比较上两组无明显差别(P>)。治疗组能显著降低面神经电图波幅损失百分比以及缩短瞬目反射 R1波的潜伏期(P<),优于对照组。结论:当归四逆汤加减方能够明显改善患者面部症状和体征,减轻患者的痛苦,并能有效改善面神经功能,是治疗Bell麻痹的有效方剂。关键词Bell麻痹;当归四逆汤加减方;House-Brackmann分级量表;面部残疾指数(FDI);电生理学检查 Clinical Research ofDangguisini Decoction inTreating BellPalsy Speeh脚.-Internal Medicine ofTraditional Chinese Medicine Anthor:Miao Lili Tutor: Zhiqiang Abstract Objective:To observe thetherapeutic effectofdangguisini decoc6伽on thepatients suffering from Bellpalsy,SO astofind new :60 patients with Bell palsy were randomly divided intothetreatmentgroup(dangguisini decoction-group n=301 and thecontrolgroup(Dahuoluo capsules·group n=30).Both were treated then pared withtheirH-B andFDI(including FDIP and FDIS)measuring scale,percentage of theamplitude loss inelectroneurography饵NoG) and thelatency ofRl-wave inblinkreflex(BR)before : Thestatisticanalysis revealed thatthetotaleffective rateofthetreatmentgroup %, while thecontrol group %.There was significantdi壕黼between them∽). After the treatment,H-B classification and the improvement of FDIP ******@3 in the Irealmentgroup are betterthan thecontrolgroup口<).Whi]e there was no significant difference inFDIS scoring changes beBveen thetwogroups口>).The treatmentgroup 锄significantly lower thepercentage ofamplitude lossin ENoG andshorten thelatency ofRl-wave inBR口<),better than the control :Dangguisini decoction can significantlyimprove symptoms andsigns offace,relieve thepatients’pain' and can effectivelyimprove facial nerve