文档介绍：西昌学院毕业设计 1 马鞭草化学成分的研究作者:孙成、李峰、李炎平、周明军指导老师:杨勇勋年级专业:( 2009 级应用化工技术) 摘要: 本论文由两部分组成,第一部分主要是对马鞭草的化学成分及药理作用作一介绍和说明; 最后一部分是马鞭草的化学成分研究。为了寻找具有抗肿瘤等生理活性的环烯醚萜类化合物,我们对马鞭草进行了化学成分研究,现通过硅胶柱色谱等方法,从马鞭草中分离得一个化合物,并根据理化性质与核磁共振光谱,鉴定化合物为马鞭草苷,此化合物的分离与鉴定为下一步的新药开发奠定了坚实的基础。关键词:马鞭草化学成分环烯醚萜苷马鞭草苷 Abstract : This paper includes two chapters: part 1 isa review of the research progress on chemical constituents and bioactivity of Verbena officinalis L., the last part is the study on the chemical constituents from Verbena officinalis L .. To find the iridoid glucosides constituents which have many bioactivities such as anticancer from Verbena officinalis L ., we investigated the chemical constituents of Verbena officinalis L .. Now, pound w as isolated From the Verbena officinalis L. by the various chromatograph y such as silica gel column. On the basis of chemical evidences and extensive spectroscopic methods, the structure of pound 1 was elucidated as verbenalin . The isolation and identify pound 1 provide a basis of exploitation a new drug. Key words: Verbena officinalis L chemical constituents iridoid glucosides verbenalin 西昌学院毕业设计 2 1马鞭草研究现状 马鞭草概述马鞭草为马鞭草科多年生植物,又名紫顶龙牙草、燕尾草等,始载于《名医别录》[1]。马鞭草通常情况下高度为 30-120 厘米,主根近木质,黄白色,有多数须根;茎四棱形,多分枝;双子叶对生;其花秋夏开放,成蓝紫色。马鞭草喜肥、喜湿润、怕涝、不耐干旱,但一般的土壤均可生长。广泛分布于中国的西南、江浙、陕西等地;其在国外分布亦广泛,主产热带美洲[2]。长期以来,马鞭草在中国被作为传统中药使用,其有清热解毒、活血散瘀、利水消肿等功效;可用于治疗疟疾、白喉、流行性感冒、咳嗽等病状。中国药典 2005 年版一部记载马鞭草用于经闭痛