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口腔粘膜溃疡类疾病 Oral Ulcerative diseases
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Introduction
BehÇet’s disease
Traumatic Ulcer & Traumatic Bulla
Recurrent Aphthous Ulcer
Summary & Questions
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Reiter’s Syndrome
I. Introduction
Ulcers are one of the mon types of lesions seen in oral mucosa.
2. The difference between ulcer and erosion.
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ulcer
erosion
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ulcer
erosion
continuity of epithelium
broken
severe
superficial
basal cells
involved
free
border
clear
unclear
diseases
RAU
Behcet’s disease
Syphilis
Pemphigus
Herpes simplex
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Comparison
Recurrent Aphthous Ulcer
• Name
recurrent aphthous ulcer RAU
recurrent aphthous stomatitis RAS
recurrent oral ulcer ROU
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• Typing Lehner’s classification
minor aphthous ulcer (MiAU)
major aphthous ulcer (MjAU)
herpetiform ulcer (HU)
• Characteristic
recidivity
self-healing
periodicity
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2. Etiology unknown
• immunity : cellular immunity, humoral immunity, complement, autoantibody
• heritage
• infection :HSV
• environment: psychology
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• denutrition :iron, copper, zinc, folic acid, Vit B12
• hyperoxide dismutase
• microcirculation disturbance :lip, nail, apex linguae
• systemic factor :ulceration of stomach、hepatitis、colonitis、diarrhoea
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3. Clinical features
minor aphthous ulcer
major aphthous ulcer
herpetiform ulcer
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