文档介绍：甲状腺球蛋白及抗体测定对甲状腺乳头状癌及结节性甲状腺肿的鉴别诊断意义
罗湘涛毛晓春( 浙江省肿瘤医院浙江杭州 310022)
【摘要】目的通过回顾性分析甲状腺乳头状癌及结节性甲状腺肿患者术前甲状腺球蛋白(TG) 及抗甲状腺球蛋白抗体(TG-Ab)水平, 探讨其对甲状腺乳头状癌及结节性甲状腺肿的鉴别诊断意义。方法将所选对象分甲状腺乳头状癌组和结节性甲状腺肿组,比较两组患者术前甲状腺球蛋白(TG) 及抗甲状腺球蛋白抗体(TG-Ab)水平。结果甲状腺乳头状癌组的TG值明显高于结节性甲状腺肿组与正常值上限,经t检验证实均有明显统计学意义,而TG-Ab值在甲状腺乳头状癌组与结节性甲状腺肿组及正常值上限比较,均无明显统计学意义。结论甲状腺球蛋白(TG)测定对甲状腺乳头状癌及结节性甲状腺肿的鉴别诊断有明显的临床意义,抗甲状腺球蛋白抗体(TG-Ab)测定对甲状腺乳头状癌及结节性甲状腺肿的鉴别诊断无明显的临床意义。
【关键词】甲状腺球蛋白(TG) 抗甲状腺球蛋白抗体(TG-Ab) 甲状腺乳头状癌结节性甲状腺肿
【中图分类号】 【文献标识码】A 【文章编号】2095-1752(2013)33-0130-02
The significance of Thyroglobulin and anti-thyroglobulin antibodies detection in differential diagnosis of Papillary Thyroid Carcinoma and Nodular Goiter
LUO xiang-tao, MAO Xiao-chun,
( Zhe jiang Cancer Hospita, Hangzhou, 310022, China)
【Abstract】 Objective To study the value of thyroglobulin (TG) and anti-thyroglobulin antibodies (TG-Ab) detection in differential diagnosis of papillary thyroid carcinoma and nodular goiter by retrospectively reviewing the TG and TG-Ab level in the patients pre-operation. Methods TG and TG-Ab level in papillary thyroid
carcinoma and nodular goiter patients pared respectively. pared with control and nodular goiter patients, TG level in papillary thyroid carcinoma patients was significantly up-regulated, while TG-Ab level showed no statistical significance in all groups. pared with TG-Ab, TG detection could provide more helpful cli