文档介绍：其水提物。松萝酸对藤黄微球菌和金黄色葡萄球菌耐药菌有较强的抑制作用。
本论文研究结果为鬼箭羽的药效物质基础研究、药理作用研究、生药和制剂的质量标准研究、临床用药以及进一步开发利用鬼箭羽药材资源提供了重要的研究基础。
关键词:鬼箭羽;挥发油;化学成分;薄层色谱鉴别;体外抑菌作用
Abstract
Euonymusalarus (Thunb.) Sieb. is a traditional Chinese medicine,and used as a drug for abdominal pain and amenorrhoea. Several studies have indieated that extraets of (Thunb.) Sieb. have antihypertensive, hypoglycemic, and central analgesic activities.
From the 80 % ethanol extract of Euonymus alatus(Thunb.)Sieb., pounds were separated by using open siliea gel,macroporous absorbent resin, sephadex LH-20, HPLC, et al. On the basis of physics-chemical properties and spectroscopic analysis, pounds were identified as follows: Hop-(22)-29- en-3β-ol (1), β-sitosterol (2), Friedelinol (3), Lupenone (4), Betulin (5), Oleanolic
acid (6), Usnic acid(7), Hexacosanoic acid (8), n-Octacosanol (9), Wilforlide A (10),
Friedelin (11), n-Octane (12), 1,30-Triacontanediol (13), β-dauricine (14),
n-Pentacosane (15), 5-Hydroxymethyl furfural (16), n-Nonane (17), Quercetin (18),
Tetracosanoic Acid (19), Squalene (20), Phenylformic acid (21), Caffeine (22).
Among them, compounds1, 4, 5, 6, 8, 12, 13, 15, 16, 17, 19, 20 and 22 are reported
from the Species for the first time. Compounds1, 5, 8, 12, 13, 15, 17, 20 and 22 are reported from this genus for the first time.
The essential oils from Euonymus alatus (Thunb.) Sieb. were extracted by steam distillation, and analyzed by GC-MS. 56 ponents were identified, their relative contents were determined and accounted for over %. It was found that the main ponents were carboxylic acid, aldehyde, ketone, terpenoid and derivatives of oxygenated terpenoid, in which the pounds were n-Hexadecanoic acid %, Analgit %, 9,12-Octadecadienoic acid %, Tetradecanoic acid %, Hexanal %, 9,12,15-Octadecadienoic acid %, Pentadecanoic acid %, Nonanal
%,Dodecanoic acid %, Hexahydrofarnesyl acetone %.
To study the effective quality co