文档介绍：F 404403
益肾舒心丸改善冠心病左室舒张功能障碍的临床研究提要
目的:研究益肾舒心丸对冠心病左室舒张功能障碍的影响和可能机
-堙。方法:观察病例总数70例,随机分为实验组40例,对照组30例。实验组f1服益肾舒心丸,伊次10克,每日3次,对照组口服硫氮罩***,每次30mg,每目3次。两纽均4周为一疗程。心功能、心绞痛、心电图疗效及中医症状疗效采用组间对比的方法。左室舒张功能指标(EV、AV、AV/EV、 Ac、DC、EAT+EDT、1/3FF)、血脂、血液流变学指标采用用药前后自身对照。7结果:益肾舒心丸能明显改善患者的心功能(P<)及左室舒张功能指标IP<),并能改善患者的心绞痛症状(P<)及心电图。中医症状改善总有效率为90%(P<)。并能有效地改善胸闷、胸痛、心慌、乏力、尿频等症状(P<),还可以降低血脂、血粘滞度等(P< )。'结论:肾虚血瘀、痰饮内停是冠心病左室舒张功能障碍的重要病机。用益肾活血、利水化痰治疗,效果良好。本研究丰富和深化了中医学治疗冠心病左室舒张功能障碍的治疗学内容,对指导临床实践具有重要的实用价值。
主题词;益肾舒心丸冠心病在室舒张功能障碍肾虚血瘀、痰饮内停临床研究/
Clinical Study on Treating Left Ventricular Diastolic Dysfunction(LVDD)
Coronary Atherosclerotic Heart Disease(CliO)by Yi Shen Shu Xin Pill
Specialty:The Study ofCuring Heart Disease by Traditional Chinese Medicine
Written by:Xu Jie
Instructed by: Shu Wen
Abstract
Objective:To study the effects and possible mechanism of YSSX pill in treating CHD :70 cases are divided into two groups
treatment group(40 cases)are treated with YSSX pill,1 09,3 times a day,while the control group(30 cases)treated with Diltiazem,30rag,3 times a weeks is a therapeutic effects of cardiac function,angina,electro—cardio—gram(ECG)
and symptom are observed between the two changs of diastolic function
ofleR ventricle fE apexes、A apexes、A/E、AC、DC、EAT+EDT、1/3FF).blood—fat and hemodynarnics indication are pared between before and after therapy. Results:YSSX pill call obviously improve the cardiac function伊<)and diastolic function of left ventricle indication(P<),the symptom of angina
fP<)and total effective rate of improving symptoms of treatment
group is 90%rP<).The YSSX pill can significantly ameliorate the symptoms such as feeling of oppression in the chest,palpitation,fatigue,frequent micturition
(P<), carl depress blood—fat and hemodynamics(P< or ),ete.
There is significant difference between the two :The mechanism