文档介绍：碳纳米管修饰电极
Research article
Received: 24 January 2011 Revised: 21 June 2011 Accepted: 21 June 2011
Drug Testing and Analysis
Published online in Wiley Online Library
() DOI
Application of multiwalled carbon nanotubes/ ionic liquid modified electrode for amperometric determination of sulfadiazine
Xiaoping Hong,a,b* Yan Zhua and Jingying Mac
A highly sensitive amperometric sulfadiazine sensor based on coating multiwalled carbon nanotubes (Ts) and Noctyl-pyridinium-hexafluorophosphate (OPPF6) ionic posite on a glassy carbon (GC) electrode is described. The Ts/posite contributed new properties to electrochemical sensors bining the advantages of both ionic liquids and Ts. Compared with bare GC electrode, the electrocatalytic activity of Ts/OPPF6 generated a greatly improved electrochemical detection of sulfadiazine including low oxidation potential, high current responses, and good antifouling performance. The oxidation peak currents of sulfadiazine obtained on the Ts/OPPF6 coated GC electrode were proportional to the concentration of sulfadiazine within the range of - with a detection limit of . Copyright © 2011 John Wiley & Sons, Ltd.
Keywords: sulfadiazine; electrochemical; multiwalled carbon nanotubes; ionic liquid
Introduction
Sulfonamides monly used as antibiotics for the therapy of urinary-tract infections, chronic bronchitis and several other bacterial infections.[1] Recently, sulfonamides have been extensively incorporated in animal feedstuff for prophylactic and therapeutic purposes due to their low cost and broad-spectrum bactericidal properties. Overdosage of veterinary sulfonamide drugs or improper medication during withdrawal time (WDT) always results in excessive drug residues found in animal derived food. However, the risk of sulfonamide drug residues existing in food products may cause undesired effects on consumers such as allergy, disorder of the hemopoietic system, carcinogenic, teratogenic action [2] and bact