文档介绍：抗凝与双联抗栓治疗冠心病合并心房颤动的效果比较
[摘要]目的分析比?^冠心病合并心房颤动使用抗凝与双联抗栓的治疗效果。方法选取2015年1月~2016年8月我院收治的100例冠心病合并心房颤动患者作为研究对象,按照双盲法将其分为研究组(n=50)和对照组(n=50)。对照组患者使用双联抗栓治疗,研究组患者使用抗凝治疗。对比分析两组患者的随访情况、质子泵抑制剂(PPI)使用率及HAS-BLED、CHADS2评分。结果两组患者的次要终点事件和出血事件发生率比较,差异无统计学意义(P>),研究组患者的主要终点事件发生率明显低于对照组,差异有统计学意义(),研究组患者的HAS-BLED评分低于对照组,差异有统计学差异(P<)。结论冠心病合并心房颤动患者实施抗凝治疗效果优于双联抗栓治疗,在有效减少患者发生出血风险的同时,提高治疗效果,临床实践应用价值较高。
[关键词]冠心病;心房颤动;抗凝;双联抗栓;效果
[中图分类号] [文献标识码] A [文章编号] 1674-4721(2018)3(a)-0054-03
parison of anticoagulation and double antithrombotic therapy in the analysis of coronary heart disease with atrial fibrillation
CUI Yue
Department of the First Internal Medicine,Yangchun People′s Hospital,Guangdong Province,Yangchun 529600,China
[Abstract]Objective To analyze pare the therapeutic effect of anticoagulant and double antithrombotic therapy in patients with coronary heart disease (CHD) and atrial fibrillation (AF).Methods A total of 100 patients with CHD and AF treated in our hospital from January 2015 to August 2016 were selected as patients were divided into research group (n=50) and control group (n=50) according to the double-blind the control group,double antithrombotic therapy was used,while in the research group,anticoagulation was situation of follow-up visits,utilization rate of proton pump inhibitor (PPI) and scores of HAS-BLED and CHADS2 paratively There was no significant difference between the two groups in secondary end point events and bleeding events (P>).The main end point event in the research group was significantly lower than that in the control group,and the difference was statistically significant (),and the patients in the research group had a st
atistically significant pared with the control group (P<).Conclusion For patients with CHD and AF,the anticoagulant effect is better than that of double antithrombotic former improves therapeutic effect and reduces the risk o