文档介绍：本文由蔡红柳刘文乔贡献
药理学 Pharmacology
Department of Pharmacology Zunyi Medical College 黄夑南教授二级教授(二级二级)
总论
General Principles
绪言 Introduction 2. 药物代谢动力学 ics 3. 药物效应动力学 Pharmacodynamics 4. 影响药物效应的因素 Factors affecting drug efficacy
第一章绪言 Introduction
一、药理学的性质和研究内容药物(drug) 1. 药物(drug) 改变或查明机体生理功能及病理的状态, 或查明机体生理功能及病理的状态可改变或查明机体生理功能及病理的状态,用于预诊断和治疗疾病的化学物质化学物质。防、诊断和治疗疾病的化学物质。 A drug
is a chemical substance that can modulate the current physiological and pathological status quo of a biological system. A chemical which is utilized for the diagnosis, prevention and cure of of an unwanted health condition (definition by FDA).
药物的来源(Source of drugs)
Ancient ●Natural products ( Plants, Animals and Minerals ) Modern ● Active principles of natural products ● Microbes ● Artificial Synthetics ● ic engineering drugs Poisons are drugs. Drugs has toxicity.
药理学(Pharmacology) 研究药物与机体相互作用及作用规律的科学 Pharmacology is the science of studying the between drugs and living systems 性质: 基础医学————临床医学基础医学————临床医学桥梁学科医学————药学医学————药学理论科学实践科学
interactions
药理学的研究内容: (1)药物效应动力学(药效学) 研究药物对机体的作用及作用机制。 The actions of the drug on the body are termed Pharmacodynamics (2)药物代谢动力学(药动学) 研究药物在机体的影响下所发生的变化及其规律,主要包括药物的吸收、分布、生物转化和排泄过程。 The actions of the body on the drug are called ics.
It mainly included in absorption, distribution, metabolism (biotransformation), excretion.
药物效应动力学(Pharmacodynamics)
作用、作用、作用机制
吸收、分布、代谢、吸