文档介绍：Chapter 13 厌氧性细菌
(anaerobic bacteria)
概述
生长和代谢不需要氧气,利用发酵获取能量
根据能否形成芽胞,可分为
厌氧芽胞梭菌属
无芽胞厌氧菌
第一节厌氧芽胞梭菌属
(Clostridium)
Clostridium
Gram-positive, spore-forming rods
Anaerobic and catalase negative
120 species
Oval or spherical spores produced only under anaerobic conditions
anic acids, alcohols, and exotoxins
Cause wound infections, tissue infections, and food intoxications
一、破伤风梭菌
()
6
Clostridium tetani
Ubiquitous in soil, it is occasionally found in intestinal flora of humans and animals.
causes tetanus (破伤风) or lockjaw, a neuromuscular disease
spores usually enter through accidental puncture wounds, burns, umbilical stumps, frostbite, & crushed body parts by contaminated soil or foreign objects such as nails or glass splinters
Tetanospasmin (破伤风痉挛毒素) – neurotoxin causes paralysis
ine booster needed every 10 years
Biological Features
Morphology
long and slender; peritrichous flagella, no capsule, terminal located
round spore (drumstick apperance), G+
Culture
obligate anaerobic; Gram(+); swarming occurs on blood agar, faint hemolysis. 血平板上呈薄膜状爬行生长
Biochemical activities (生化反应)
activities: does not ferment any carbohydrate and proteins
Resistance (抵抗力)
tolerate boiling for 60 min. alive several ten years in soil