三羧酸循环.ppt

文档介绍：三羧酸循环TheCitricAcidCycleThetricarboxylicacid(TCA)cycleTheTCACycle—ABriefSummaryTheentryofnewcarbonunitsintothecycleisthroughacetyl-(fromglycolysis),metabolicenergyiscapturedintheformofATP,NADH,andenzyme-boundFADH2(symbolizedas[FADH2]).,notonlyforthestorageformsoffuels,butalsoforthebuildingblocksofmanyothermoleculessuchasaminoacids,nucleotidebases,cholesterol,andporphyrin(ponentofheme).monpathwayfortheoxidationoffuelmolecules—aminoacids,fattyacids,,alsocalledthetricarboxylicacid(TCA)cycleortheKrebscycle(afteritsdiscoverer,HansKrebs).onditions,,thereactionsofthecitricacidcycletakeplaceinsidemitochondria,incontrastwiththoseofglycolysis,:Oxidativeplex(PDC)aclusterofenzymes—multiplecopiesofeachofthreeenzymes—:pyruvatedehydrogenase(E1),dihydrolipoyltransacetylase二氢硫辛酸转乙酰基酶(E2),anddihydrolipoyldehydrogenase二氢硫辛酸脱氢酶(E3)—eachpresentinmultiplecopies.