以导电性纳米碳管为支架的组织工程神经研究进展.doc

文档介绍：中国修复重建外科杂志2011年11月第25卷第11期

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以导电性纳米碳管为支架的组织工程神经研究进展
向宁王光林
【摘要】目的对目前国内外导电性纳米神经组织工程,尤其是导电性纳米碳管(T)相
关研究的进展进行综述。方法 T 研究的相关文献并进行综
述。结果导电性纳米神经组织工程相关研究目前在周围神经损伤修复的基础研究方面已经取得一定进展,导电性
CNT 能促进雪旺细胞附着、生长和增殖,并能模拟神经髓鞘的导电功能,在刺激和引导神经生长及轴突再生方面起重要作
用。结论 T 在周围神经损伤的修复和功能重建方面有着独特优势,有望为周围神经损伤修复与功能重建
提供新的治疗方法。
【关键词】神经组织工程导电性纳米碳管纳米技术神经修复
RESEARCH PROGRESS OF NEURAL TISSUE ENGINEERING BASED ON ELECTRICALLY CONDUCTIVE
CARBON NANOTUBE SCAFFOLD/XIANG Ning, WANG Guanglin. Department of Orthopaedics, West China Hospital,
Sichuan University, Chengdu Sichuan, 610041, . Corresponding author: WANG Guanglin, E-mail: wglfrank@
【Abstract】
Objective
To review the basic researches and the cl inical appl ication of the nano-neural tissue
engineering materials, especially the electrically conductive carbon nanotubes (CNT).
Methods
The l iterature concerning
the basic and cl inical researches of the conductive materials of nano-neural tissue engineering, especially the electrically
T were reviewed.
Results
The researches of conductive materials of nano-neural tissue engineering have made
some progress, the electrically T can not only promote Schwan cells’ adhension, migration, and prol iferation,
but also mimic the function of electric conductivity of neural myel in and enhance neurite growth and regeneration. So the
electrically T make great sense in stimulating and dir