文档介绍：学术探讨
脑血管支架置入后凝血系统和细胞因子的变化★
李志鹏,吴鹏飞,景治涛,王运杰
Changes in coagulation system and cytokines following intravascular stenting
Li Zhi-peng, Wu Peng-fei, Jing Zhi-tao, Wang Yun-jie
Department of Neurosurgery, First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Li Zhi-peng★, Studying for master’s degree, Department of Neurosurgery, First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
lzp0408@
Correspondence to: Wang Yun-jie, Chief physician, Department of Neurosurgery, First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Received:2008-09-22
Accepted:2008-09-27
中国医科大学附属第一医院神经外科,辽宁省沈阳市 110001
李志鹏★,男,1982年生,辽宁省沈阳市人,汉族,中国医科大学在读硕士,主要从事脑血管疾病的研究。
lzp0408@
通讯作者:王运杰,男,主任医师,中国医科大学附属第一医院神经外科,辽宁省沈阳市 110001
中图分类号: R743
文献标识码: B
文章编号: 1673-8225
(2008)44-08758-04
收稿日期:2008-09-22
修回日期:2008-09-27
(54200810240014/
WJY·A)
Abstract: Intravascular stent as a foreign body exhibits obvious reaction following implantation, such as activation of coagulation system and elevation of serum C-reactive protein, inflammatory marker. After platelet is activated, P-selectin binds to the glycoprotein ligand 1 expressed on leukocyte, and forms congeries on the leukocyte. In addition, interleukin-1β, interleukin-6 and tumor necrosis factor-α are greatly secreted. The two factors are main reasons for