文档介绍：甲亢指南
Subclinical Hyperthyroidism: When to Treat
Preparation of patients with GD for I131 therapy
Administration I131 in the treatment of GD
Patient follow-up after I131 therapy for GD
Treatment of persistent Graves’ hyperthyroidism following radioactive iodine therapy
I131 Guidelines
with GD who are at increased risk plications due to worsening of hyperthyroidism (., those who are extremely symptomatic or have free T4 estimates 2–3 times the upper limit of normal) should be treated with beta-adrenergic blockade prior to radioactive iodine therapy.
with methimazole prior to radioactive iodine therapy for GD should be considered in patients who are at increased risk plications due to worsening of hyperthyroidism (., those who are extremely symptomatic or have free T4 estimate 2–3 times the upper limit of normal).
Preparation of patients with GD for I131 therapy
MENDATION
Technical remarks
MMI should be discontinued 3–5 days before the administration of radioactive iodine, restarted 3–7 days later, and generally tapered over 4–6 weeks as thyroid function normalizes.
radiation should be administered in a single dose (typically 10–15 mCi) to render the patient with GD hypothyroid.
2. A pregnancy test should be obtained within 48 hours prior to treatment in any female with childbearing otential who is to be treated with radioactive iodine.
Administration I131 in the treatment of GD
MENDATION
1. A special diet is not required before radioactive iodine therapy, but excessive amounts of iodine, including iodine-containing multivitamins, should be avoided for at least 7 days.
2. Conception should be delayed for 4–6 months in women to assure stable euthyroidism (on thyroid hormone replacement following essful thyroid ablation) and 3–4 months in men to allow for turnover of sperm production.
3. In breast-feeding women, radioactive iodine therapy should not be administered for at least 6 weeks after lactation stops to