循证医学-系统评价和meta分析.ppt

文档介绍：系统评价和Meta分析SystematicReviewandMeta-analysis南昌大学公共卫生学院黄鹏问题的提出对上述结果,是不是难以判断并选择?用X线进行乳腺癌筛查MammographyforbreastcancerisanestablishedscreeningmethodIsscreeningwithmammographyjustifiable?Gotzsche&Olsen[ochraneCentre],withover182,000womenrandomizedTheauthorsfoundthatnotrialdatawereofhighqualityTwowereofmediumquality,,(95%,)Theyconcludedthat“screeningforbreastcancerwithmammographyisunjustified”TheUSPreventiveServicesTaskForcereviewedthesamesetoftrialsRecently,a2001CochraneCollaborationreviewofthesametrialsconcludedthatsixoftheeighttrialswere"flawed"orof"poorquality"-binedtrialswassizableandstatisticallysignificant:thesummaryrelativerisk(RR)(95percentCI,-).mendsscreeningmammography,withorwithoutclinicalbreastexamination,every1-.prehensivesystematicreviewin1997Theyidentified37publishedstudiesthatreportedriskoflungcanceramonglifelongnon-ordingtothehusband’ssmokingstatus