文档介绍：RoleRole ofof ModernModern RadiotherapyRadiotherapy
inin OncologicOncologic PracticePractice
CatherynCatheryn Yashar,Yashar, MDMD
UniversityUniversity ofof California,California, SanSan DiegoDiego
OverviewOverview
BriefBrief HistoryHistory
IMRTIMRT
IGRTIGRT
IncorporationIncorporation ofof NovelNovel ImagingImaging intointo
TreatmentTreatment PlanningPlanning
BreastBreast brachytherapybrachytherapy
SRSSRS –– StereotacticStereotactic RadiosurgeryRadiosurgery
Wilhelm Roentgen (1845-1923)
RadiationRadiation OncologyOncology
TwoTwo monthsmonths (!!!)(!!!) afterafter thethe discoverydiscovery ofof xx--
raysrays thethe 11st patientpatient waswas treatedtreated withwith
radiationradiation therapytherapy (RT)(RT)
RoseRose LeeLee aa 6565 yearyear oldold womanwoman withwith
locallylocally recurrentrecurrent breastbreast cancercancer
TreatingTreating physicianphysician waswas aa ChicagoChicago
medicalmedical studentstudent namednamed EmilEmil GrubbeGrubbe
TreatedTreated inin GrubbeGrubbe’’ss lamplamp factoryfactory onon
HalsteadHalstead StreetStreet inin DowntownDowntown ChicagoChicago
TheThe 11stst RadiationRadiation OncologistOncologist
Emil Grubbe (1875-1960)
X-ray Mania
Public Demonstration 1902
1st patient treated
with the 1st megavoltage
unit in the USA
Stanford University
1955
Recurrent
Retinoblastoma
Patient is
alive and well
with good vision today
puter-Controlled
Linear Accelerators
(6 and 18 MV photons
multiple electron energies)
1990s
RadiationRadiation OncologyOncology
DespiteDespite suchsuch advancements,advancements, basicbasic
approachapproach toto RTRT planningplanning andand deliverydelivery
hashas remainedremained relativelyrelatively unchangedunchanged
AfterAfter sitesite isis selected,selected, limitedlimited setset ofof
beamsbeams (typically(typically 22--4)4) areare chosenchosen
AA planplan isis generatedgenerated byby iterativelyiteratively varyingvarying
beambeam parametersparameters (