文档介绍：BRITISH JOURNAL OF PSYCHIATRY (2004), 184, 223^230
Neural response to emotional prosody and Trafford NHS Trust) and the
Psychiatry Department at Manchester
in schizophrenia and in bipolar affective disorder Royal Infirmary (Central Manchester
NHS Trust). The subjects’ demographic
statistics are summarised in Table 1.
RACHEL L. C. MITCHELL, A ELLIOTT, MARTIN BARRY,
Because gender and handedness each may
ALAN CRUTTENDEN and PETER W. R. WOODRUFF influence lateralisation of the brain for
language (Beaton, 1997), only male sub-
jects who were right-handed (t,
1970) were studied. We excluded subjects
with a history of hearing difficulties; those
who did not speak English as their first lan-
Background Evidence suggests a Patients with schizophrenia demonstrate guage; any who were unable to consent;
reversal ofthe normalleft-lateralised relatively greater activation of the right those who gave a self-report of neurological
middle temporal gyrus, compared with the disorders; those with a history of alcohol or
response to speech in schizophrenia.
left, when listening to normal speech drug misuse, head injuries or long periods
Aims Totestthe brain’sresponse to (Woodruff et al, 1997; Lennox et al, of unconsciousness; and those in whom
2000; Sommer et al, 2001). The neural ic resonance scanning was contra-
emotional prosody in schizophrenia and
response t