文档介绍：Polygenic Disorders
Polygenic Disorders:
由两对以上等位基因和环境因素共同作用所致的疾病,称为多基因病。
Polygenic Disorders are those which result from an interaction between multiple genes and multiple environmental factors.
Section 1
Polygenic Inheritance
一、Definition
1. ic basis: multiple genes
3. Minor gene,Additive effect
2. Codominance
4. multiple environmental factors
一些遗传性状或遗传病受两对或更多对等位基因控制,每对基因彼此间没有显性与隐性的关系,而是共显性。每对等位基因对表型的效应都很小,但是各对基因的作用有累加效应,此外,这些遗传性状或遗传病也受环境因素的作用,这种遗传方式称为多基因遗传(poly-genic inheritance)。
二、Characteristics
Qualitative Trait and
Quantitative Trait
Qualitative Trait
Monogenic trait
Pituitary
dwarfism
Qualitative Trait
Monogenic trait
120 cm 165 cm
aa AA OR Aa
Height of pituitary dwarfism & normal