文档介绍：甲状腺癌术前辅助检查对于病理分型和术式的选择意义
作者:凌瑞,李南林,张震,王岭,杨华
【关键词】,甲状腺肿瘤/病理学
【Abstract】 AIM: To assess the pathology type of thyroid nodules on the basis of clinical manifestation and other parameters of preoperative examination and to investigate its relationship with operation mode. METHODS: Using paraffin embedded tissue sections as the gold standard of diagnosing thyroid carcinoma, we divided 483 cases into four groups: group Ⅰ was papillary thyroid carcinoma, group Ⅱ was follicular thyroid carcinoma, group Ⅲ was undifferentiated carcinoma and group Ⅳ was medullary carcinoma. Ultrasonographic scanning was used to analyze the clinical manifestations and the relationship between the clinical manifestations and pathology type was assessed. RESULTS: Of the 483 cases, the 4 groups accounted for %, %, % and %, respectively. There was no significantly statistical correlation between the age and malignancy of the thyroid nodules between group Ⅰ, group Ⅱ and group Ⅳ, but there was significantly statistical correlation between group Ⅰ, group Ⅱ, group Ⅳ and group Ⅲ. The same was true of the diameter of the nodules. The cases with diameter >4 cm were more likely to have undifferentiated carcinoma. There was no significantly statisti
cal correlation between group Ⅰ, Ⅱ, Ⅲ and Ⅳ group for the number of nodules, but significantly statistical correlation was found between group Ⅰ/Ⅱ and group Ⅲ/Ⅳ in cold nodules and the intumescence of lymph node in the neck. The examination of thyroid function was not very helpful in the pathological classification of thyroid cancer. CONCLUSION: Preoperative examination is important in determining the pathological type and choosing proper surgical mode.
【Keywords】 Thyroid neoplasms/pathology; biopsy, needle; thyroid neoplasms/surgery
【摘要】目的: 探讨甲状腺结节的临床特征,结合术前辅助检查对判断甲状腺恶性肿瘤病理分型的作用,并根据病理分型采取适当的手术方式. 方法: 以术后石蜡病理切片结果作为确诊甲状腺癌的金标准,将483例甲状腺癌患者分为4组,分别为乳头状腺癌(Ⅰ组)、滤泡状腺癌(Ⅱ组)、未分化癌(Ⅲ组)和甲状腺髓样癌(Ⅳ组),对各组的临床特征、甲状腺核素扫描、甲状腺B超检查和甲状腺功能检查结果进行分析,探讨其与恶性肿瘤病理分