文档介绍：黑色素瘤分期料慧眉刚呼疟恩豌命滩蛾提拓赁瞬婆叛院伯裕挝稠悍悠兑铡帆具县吁艺药黑色素瘤分期黑色素瘤分期HISTORICALASPECTSOFMELANOMASTAGING蒋绍八煽测类缩列摔茂涸啡豆梦骸洞娶锚枪夸淤障酸罪睹割充验值骆织钵黑色素瘤分期黑色素瘤分期AllenandSpitzintheirclassicpaperpublishedin1953,,:patientswithdistantmetastasespatientswithregionallymphnodemetastasesclinicallydetectedandhistologicallyprovenpatientswithclinicallynegativebuthistologicallypositiveregionallymphnodespatientswithprimarydiseaseonly,,cleardifferencesinsurvivalhadbeendemonstratedinthreegroupsofpatientsonthebasisofclinicalassessment—thosewithprimarydiseaseonly,thosewithregionallymphnodemetastases,-eerandDasGuptafromtheMemorialSloan-,,whichmeansinsitumelanoma,notinfiltratingthroughthebasalcelllayer;levelII,infiltrationintothepapillarydermis;levelIII,infiltrationasfaras,butnotintothereticulardermis;levelIV,infiltrationintothereticulardermis;levelV,,Breslowdemonstratedthattumorthicknesswasanimportantprognosti