文档介绍:118例乳腺癌患者预后相关因素分析
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【摘要】目的分析118例乳腺癌患者临床病理特征、治疗方法与预后间的相关性,明确影响乳腺癌预后的相关因素。方法收集整理2002-2004年间宁夏医科大学附属医院收治的118例乳腺癌患者的临床病理资料。结果 %。肿块大小、腋窝淋巴结转移数目及临床分期与患者生存率呈负相关(P<)。ER、PR、C-erbB-2均为阴性表达者(“三阴”乳腺癌)生存率较非“三阴”乳腺癌明显降低(P=)。根治术后行内分泌治疗者较未予内分泌治疗者5年生存率明显提高(P=)。术后放疗者较未予放疗者5年生存率明显提高(P=)。结论肿块大小、腋窝淋巴结转移数目、临床分期、“三阴”乳腺癌以及术后进行内分泌、放射治疗均与预后密切相关。其中肿块大小、腋窝淋巴结转移数目和临床分期为影响乳腺癌患者预后的独立危险因素。
【关键词】乳腺癌;生存率;预后因素
Abstract: Objective To summary and analyze the correlation between prognosis and pathological character and treatments in 118 breast cancer patients. Methods The clinical and pathological data were reviewed in 118 breast cancer patients between 2002 to 2004 in the affiliated hospital of Ningxia medicial university. The SPSS software was used to analyze the prognostic factors. Results The 5 years survival rate of the 118 cases is %. Based on the analysis, tumor size, number of positive axillary lymph nodes and clinical stage showed significantly negative correlation with the 5 years survival rate(P<). The cases that were not expressed ER, PR, CerbB2 at all(the TripleNegative Breast Cancer ) had a significantly lower survival rate than others(P=). The ones who got endocrine therapy had a significantly higher 5 years survival rate than the ones who did not(P=). And the patients who got postoperation