文档介绍：70例小儿福氏痢疾杆菌耐药性分析
(作者:___________单位: ___________邮编: ___________)
【摘要】目的分析福氏痢疾杆菌的发病特点及临床耐药性的系统分析,帮助临床合理选择抗生素,及时有效的治疗小儿细节性痢疾。方法对本院2011年1—12月70例小儿腹泻病(含有黏液及脓血便)的大便,挑取含有黏液部分及脓血粪便,30min内送检,选用S-S培养方法。结果送检标本培养结果为70例福氏志贺菌。结论细菌性痢疾发病有明显的地域性及季节性。大多数是农村患儿,发病季节3、4月份发病患儿较少,6、7、8、9为发病高峰,10月份发病相对较少,但培养的福氏志贺菌,药敏试验耐药率高。
【关键词】福氏志贺菌;药敏试验
[Abstract]ObjectiveTo analyze the Shigella flexneri clinical characteristics and antimicrobial resistance of clinical system analysis,for the clinical reasonable choice of antibiotics, timely and effective treatment of pediatric details of our hospital,70 cases children with diarrhea of - in ( containing mucus and pus and blood stool ), collected stool with mucus and pus and blood, checked in 30 minutes with S-S cultivation specimens were Shigella flexneri. ConclusionThe incidence of bacillary dysentery were obvious regional and seasonal. From March to April, there is less morbidity, in June, July, August, September is the peak,
the incidence is relatively less in October, Shigella flexneri has high drug resistance rate.
[ Key words]Shigella flexneri; drug sensitivity test
志贺菌属是人类细菌性痢疾最为常见的病原菌,细菌性痢疾是由志贺菌属引起的肠道传染病。其中在我们国家流行的多数为福氏志贺菌[1],其生物学性状:~,长为2~3μm革兰阴性的短小杆菌。无芽孢、鞭毛及荚膜,有菌毛。有13个血清型,包括B1-6,x,y变型;亚型包括1a,1b,2a,2b,3a,3b,3c,4a,4b。致病物质为侵袭力和内毒素。志贺菌侵袭人体后,细菌裂解,产生大量内毒素和少量外毒素。志贺菌内毒素从肠壁吸收入血,引起发热,毒血症及微循环障碍。内